MOTS-c

Metabolic

Also known as: Mitochondrial ORF of Twelve S rRNA Type-c

A mitochondrial-derived peptide that regulates metabolic homeostasis and exercise-mimetic effects.

Dose in studies
5-10 mg per week
Frequency
1-2x weekly
Cycle length
8-12 weeks on, 4 weeks off
Half-life
6-8 hours
Research level
2/5 – Limited research

MOTS-c dosage chart

Frequently asked questions about MOTS-c

What is MOTS-c?

A mitochondrial-derived peptide that regulates metabolic homeostasis and exercise-mimetic effects.

What is the half-life of MOTS-c?

The half-life of MOTS-c is 6-8 hours.

What dosage of MOTS-c has been studied?

Described in research: 5-10 mg per week, frequency: 1-2x weekly. This is not a medical recommendation.

How long is a MOTS-c cycle?

Typical cycle length in studies: 8-12 weeks on, 4 weeks off.

What are the side effects of MOTS-c?

Injection site reactions: Mild redness and soreness at injection site. Standard peptide injection side effect. Rotate sites and use proper technique. · Transient fatigue: Brief tiredness after injection as cellular metabolism adjusts. Typically resolves within 1-2 hours. · Mild GI discomfort: Slight nausea or stomach upset, particularly with higher doses. Taking after food may help. · Muscle…

How well researched is MOTS-c?

Limited research (2/5). Few, small or uncontrolled human data; mostly animal studies.

Comparisons