SS-31 vs. MOTS-c
Head-to-head comparison based on the profiles in the PepCycle library.
| Attribute | SS-31 | MOTS-c |
|---|---|---|
| Class | Mitochondrial | Metabolic |
| Description | A cell-permeable peptide that targets cardiolipin in the inner mitochondrial membrane to reduce oxidative damage. | A mitochondrial-derived peptide that regulates metabolic homeostasis and exercise-mimetic effects. |
| Dose in studies | 10-40 mg per day | 5-10 mg per week |
| Frequency | Daily | 1-2x weekly |
| Half-life | 1-2 hours | 6-8 hours |
| Cycle length | 4-12 weeks based on indication | 8-12 weeks on, 4 weeks off |
| Research level | 3/5 – Moderate research | 2/5 – Limited research |
SS-31: full profile · MOTS-c: full profile
Values from research literature – not medical advice.