Glutathione
Anti-Aging
Also known as: GSH, L-Glutathione, Reduced glutathione
Tripeptide (glutamate–cysteine–glycine) and the body's main intracellular antioxidant. Used in research on oxidative stress, liver support and skin brightening.
- Dose in studies
- Studied: 250–1,000 mg/day oral; 600–1,200 mg IV/IM
- Frequency
- Oral daily; injections 1–3× per week in studies
- Cycle length
- 4–12 weeks in studies
- Half-life
- ~10 minutes in plasma (IV)
- Research level
- 3/5 – Moderate research
Frequently asked questions about Glutathione
What is Glutathione?
Tripeptide (glutamate–cysteine–glycine) and the body's main intracellular antioxidant. Used in research on oxidative stress, liver support and skin brightening.
What is the half-life of Glutathione?
The half-life of Glutathione is ~10 minutes in plasma (IV).
What dosage of Glutathione has been studied?
Described in research: Studied: 250–1,000 mg/day oral; 600–1,200 mg IV/IM, frequency: Oral daily; injections 1–3× per week in studies. This is not a medical recommendation.
How long is a Glutathione cycle?
Typical cycle length in studies: 4–12 weeks in studies.
What are the side effects of Glutathione?
Generally well tolerated · Injection: local irritation, rare allergic reactions · Oral: bloating, cramps · Inhaled form can trigger bronchospasm in asthmatics · Long-term safety of high-dose IV use for skin lightening is not established (warnings e.g. from the Philippine FDA)
How well researched is Glutathione?
Moderate research (3/5). Several controlled human studies or approval in a niche indication; evidence still patchy.