5-Amino-1MQ
Metabolic
Also known as: 5-Amino-1MQ, 5-Amino 1MQ, NNMT Inhibitor
A small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that boosts cellular NAD+ levels by blocking the enzyme responsible for NAD+ degradation. Promotes fat metabolism, increases energy expenditure, and supports metabolic health — often called a "fat loss peptide" though technically a small molecule.
- Dose in studies
- (Only Researched in Mice) 50-150 mg/day oral (capsule). Typical: 100 mg/day. Users Report 2.5 - 5 mg daily for Humanresearch
- Frequency
- Once daily or split into 2 doses (morning + midday)
- Cycle length
- 8-12 weeks on, 4 weeks off. Can be used in cycles or continuously at maintenance dose.
- Half-life
- Oral bioavailability: good | Plasma half-life: ~4-6 hours
- Research level
- 1/5 – Very limited research
Frequently asked questions about 5-Amino-1MQ
What is 5-Amino-1MQ?
A small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that boosts cellular NAD+ levels by blocking the enzyme responsible for NAD+ degradation. Promotes fat metabolism, increases energy expenditure, and supports metabolic health — often called a "fat loss peptide" though technically a small molecule.
What is the half-life of 5-Amino-1MQ?
The half-life of 5-Amino-1MQ is Oral bioavailability: good | Plasma half-life: ~4-6 hours.
What dosage of 5-Amino-1MQ has been studied?
Described in research: (Only Researched in Mice) 50-150 mg/day oral (capsule). Typical: 100 mg/day. Users Report 2.5 - 5 mg daily for Humanresearch, frequency: Once daily or split into 2 doses (morning + midday). This is not a medical recommendation.
How long is a 5-Amino-1MQ cycle?
Typical cycle length in studies: 8-12 weeks on, 4 weeks off. Can be used in cycles or continuously at maintenance dose..
What are the side effects of 5-Amino-1MQ?
Mild GI discomfort: Stomach upset including mild nausea and bloating during the first week. Usually resolves as the body adjusts to metabolic changes. · Elevated body temperature: Slight thermogenic effect causing warmth. A sign the compound is working. Usually well-tolerated. · Headache: Tension headaches reported in ~15% of users during initial dosing. Adequate hydration minimizes this. ·…
How well researched is 5-Amino-1MQ?
Very limited research (1/5). Preclinical data only (cell or animal models) or no published human studies.