Semax vs. Dihexa

Head-to-head comparison based on the profiles in the PepCycle library.

AttributeSemaxDihexa
ClassNootropic PeptidesNootropic
DescriptionA synthetic peptide derived from ACTH(4-10), developed for cognitive enhancement and neuroprotection with minimal hormonal effects.A potent cognitive-enhancing peptide derived from angiotensin IV with remarkable memory-enhancing properties.
Dose in studies200-600 mcg 1-3x daily (intranasal)10-20 mg oral or 0.5-1 mg subcutaneous
Frequency1-3x daily for 2-4 weeksDaily during cognitive enhancement cycles
Half-life~30 seconds to few minutes12 hours
Cycle length2-4 weeks on, 1-2 weeks off4-8 weeks on, equal time off
Research level2/5 – Limited research1/5 – Very limited research

Semax: full profile · Dihexa: full profile

Values from research literature – not medical advice.