Melanotan I vs. Melanotan II

Head-to-head comparison based on the profiles in the PepCycle library.

AttributeMelanotan IMelanotan II
ClassDermatologicalCosmetic Peptides
DescriptionSynthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) that promotes melanogenesis for photoprotection research.A synthetic analog of alpha-melanocyte-stimulating hormone researched for tanning effects and other melanocortin-related properties.
Dose in studies0.5-1 mg per day during loading0.25-0.5 mg per day during loading
FrequencyDaily during loading, then maintenanceDaily during loading, then weekly maintenance
Half-life30 minutes~1 hour
Cycle length4-6 weeks loading, then maintenance2-4 weeks loading, then maintenance as needed
Research level4/5 – Well researched2/5 – Limited research

Melanotan I: full profile · Melanotan II: full profile

Values from research literature – not medical advice.